In her opening monologue at the Golden Globes, host Nikki Glaser poked fun at Diddy and Ben Affleck.

Golden Globes, watch out – Nikki Glaser is here to host.

Ozempic's biggest night was celebrated by Glaser, 40, who opened the show with a nod to weight-loss medication.

During a live broadcast from the Beverly Hilton hotel in Beverly Hills, Calif., Glaser praised Zendaya's performance in "Challengers," where she portrays a tennis star caught in a romantic entanglement with her husband and ex-boyfriend.

"The movie was more sexually charged than Diddy's credit card," Glaser said. "I know, I'm upset too. The after party won't be as good."

Glaser quipped that Stanley Tucci would have to host now instead of using baby oil.

Officials confirmed to Planet Chronicle Digital that on March 25, Sean ‘Diddy’ Combs' homes in Los Angeles and Miami were raided as part of a federal human trafficking investigation.

According to the federal indictment, authorities allegedly seized various "Freak Off" supplies, including narcotics and over 1,000 bottles of baby oil and lubricant during the search.

A top star was unexpectedly added to Glaser's list of nominated films.

Ben Affleck does not use the words "Wicked," "Queer," and "Nightbitch" when he orgasms, according to Glaser.

Jennifer Lopez and Affleck are currently going through a divorce.

Glaser reflected on the 22 years of effort she put into her career before the show.

Glaser began her career on 'Last Comic Standing' while in college, before moving on to shows with MTV and Comedy Central.

Ricky Gervais gave her crucial advice about hosting the Golden Globes.

"Gervais had assured her, "You'll excel," she recalled. "You're not like the others.""