Gary Sinise left Hollywood for Nashville after his son and wife were diagnosed with cancer.

Gary Sinise left Hollywood to prioritize his family's well-being.

In 2021, Sinise left Los Angeles due to his family's cancer battles, which included his son and wife.

During that time, we were fighting cancer, as shared by Sinise.

Sinise, who released his son's posthumous album "Resurrection & Revival: Part 2," previously stated that his move to Nashville was driven by both not having to pay state income tax in Tennessee and having his band, the Lt. Dan Band, nearby.

In a recent interview, Sinise revealed that he paused his acting career in 2019 to prioritize his family's safety during a time of uncertainty.

WATCH: GARY SINISE EXPLAINS WHY HE LEFT LA FOR NASHVILLE

"My wife and son were both diagnosed with cancer within two months of each other. My dad had a stroke, leaving my mom alone, and I had to take care of her while also dealing with my own hands full."

Although Sinise's wife has been cancer-free after going into remission, he revealed that his son's battle with cancer was particularly challenging. Sinise's son was diagnosed with cancer in 2018.

"Our son was battling cancer without a cure, which required constant efforts to find treatments and medical professionals who could help him. As time passed, his condition worsened, necessitating increasing amounts of care."

This year, his son, McCanna "Mac" Sinise, passed away at the age of 33 from a rare form of cancer known as chordoma.

Gary Sinise, the founder of the Gary Sinise Foundation, wrote on the charity's website that chordoma is a rare cancer that affects only about 300 people in the U.S. annually.

Mac was "happy at the end of his life," according to Sinise, despite the family being deeply affected by his death.

"Watching Mac enjoy the process of recording an album last May and seeing him achieve his goal of creating a full album from that music brought me a lot of joy."

On what would have been Mac's 34th birthday, "Resurrection & Revival: Part 2" began shipping to fans who preordered the album, as Sinise shared the importance of fulfilling his son's final wish to release his music.

"I discovered this music on his files and realized how much love he put into it."

Despite being a graduate of USC Thorton School of Music and having a passion for drumming, composition, and songwriting, Mac's disability prevented him from continuing to play the drums or piano.

WATCH: GARY SINISE DISCOVERED LATE SON’S UNRELEASED MUSIC AFTER HIS DEATH

The father-son musical duo had performed together multiple times before Mac's passing. Sinise reminisced about those special moments with Planet Chronicle Digital.

"He is an exceptional drummer with a natural talent. He is solid and fun to play with."

Before his death, Mac worked on music projects for documentaries and films.

""He shared with me some music he'd written for the movie, and it moved me deeply. As I listened, I discovered other pieces he'd hidden away that I'd never known existed," he said."

Mac, who was the assistant manager of education and outreach at the Gary Sinise Foundation, stepped down in 2020 to focus on his rehabilitation and recovery as he prepared for his fifth spinal surgery.

The Gary Sinise Foundation supports veterans and first responders through customized programs that enhance and unite communities.

In 2011, Sinise established his charity, prior to which he had worked on various films and TV shows, including "Forrest Gump."

Reflecting on his character, Lt. Dan, in the iconic film that celebrated its 30th anniversary, Tom Hanks pondered what it was like being part of the movie.

"Being on set was always enjoyable, yet demanding work. It could get pretty emotional and challenging at times. However, it always felt rewarding to be part of something meaningful."

"Did we know it would become a great classic? I don't think any of us thought that, but after the movie was embraced by the public, it became such a big hit."

"Forrest Gump," which came out in 1994, has won six Oscars, including Best Picture, Best Actor, Best Director, Best Visual Effects, Best Adapted Screenplay, and Best Film Editing.

Mykelti Williamson, who played Benjamin Buford "Bubba" Blue, is among the cast members that Sinise kept in touch with after filming.

"I'm in touch with Mykelti Williamson. We stayed friends all those years, played golf all the time, and became very good friends."

Lt. Dan Band, inspired by his "Forrest Gump" character, was named after his role since he started visiting troops overseas for his foundation.