Overdoses of a drug 100 times more potent than fentanyl have increased in the past year, according to a warning from the CDC.

The CDC is warning of the rise of an even deadlier drug, which has been making headlines for driving overdose deaths.

In 2019, approximately 69% of U.S. overdose deaths were linked to illegally manufactured fentanyls (IMFs), including carfentanil, a highly potent variant of fentanyl, according to a CDC alert on December 5.

The number of deaths from carfentanil increased by over 700% in one year, with 29 fatal overdoses occurring between January and June 2023, compared to 238 in the same time frame in 2024.

The data regarding unintentional drug overdoses in the states was obtained from the CDC's State Unintentional Drug Overdose Reporting System (SUDORS).

The number of overdose deaths in 2024 could be higher than the preliminary estimate, the agency noted.

The CDC noted that the drug carfentanil-linked deaths had "largely disappeared" since an outbreak in 2016 and 2016 until its recent reemergence.

The CDC is urging "intense surveillance" of stronger opioids, including carfentanil, due to the rise in fatal overdoses.

The prevalence of a drug is likely due to its high profitability, as stated by Dr. Chris Tuell, clinical director of addiction services at the University of Cincinnati College of Medicine.

He informed Planet Chronicle Digital that minute quantities can generate numerous doses.

"Carfentanil, a synthetic opioid, is easier to manufacture in illicit labs compared to heroin, which requires a plant like opium."

Why is carfentanil so dangerous?

Tuell confirmed that carfentanil is 10,000 times more potent than morphine and 100 times more potent than fentanyl.

Respiratory failure can be caused by even a small amount, he said.

Fentanyl and carfentanil are often combined with other substances, like benzodiazepines, cocaine, and opioids, increasing the risk of unintentional overdoses, as stated by Tuell.

"The other drugs can easily mistake carfentanil for cocaine and heroin," he cautioned.

"Even a small amount can be fatal, as it can cause respiratory failure."

"A small quantity can enhance the effectiveness of a drug blend, resulting in a more intense and prolonged high."

Drug users with a high tolerance to opioids are often drawn to carfentanil due to its stronger effects, despite the risks involved.

How is the drug administered?

Carfentanil can be injected, mixed with other opioids or heroin, or inhaled in powder form, according to Tuell.

""Be cautious when inhaling drugs as it can enter the bloodstream and cause an overdose, either intentionally or accidentally," Tuell advised."

Prescription medication-like pills can sometimes contain carfentanil, an expert stated.

He warned that carfentanil can be deadly if administered through certain routes at a dosage of 2 milligrams.

What parents should know

Tuell warned that children are increasingly being exposed to artificial intelligence and deepfakes, which can be easily mistaken for legitimate prescription medications.

The expert highlighted the significance of open communication and education in safeguarding children from the risks of illegal drugs.

Advise your child about the dangers and risks of drug use, including synthetic opioids like carfentanil.

Tuell advised that parents should monitor and supervise their children, be aware of their social circles, and limit unsupervised online activities.

He added that 84% of individuals with a substance use disorder also have a co-occurring mental health issue.

"Obtaining mental health services for your child could aid in resolving the underlying causes of their substance use disorder."

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The CDC urged specific measures to prevent deaths from illegally manufactured fentanyls, including enhancing the distribution of risk reduction tools, expanding access to and retention of treatment for substance use disorders, and preventing drug initiation.

The Drug Enforcement Administration (DEA) was contacted by Planet Chronicle Digital for comment.