In 2024, GoodRx reported that 19 drug approvals had a significant clinical impact.

These medications and vaccines, deemed "influential" by the FDA, were approved this year.

In 2024, GoodRx reported that 19 drug approvals had a significant clinical impact.
In 2024, GoodRx reported that 19 drug approvals had a significant clinical impact.

2024 brought some major advancements in medicine.

This year, the FDA approved innovative drugs such as Tryvio for high blood pressure, Neffy for severe allergic reactions, and Dupixent for chronic obstructive pulmonary disease (COPD).

According to GoodRx, a California-based digital health care platform, these medications are expected to have a significant clinical impact on those who require them.

In 2024, GoodRx published a list of the 19 most significant drug and vaccine approvals, which included both new treatments for specific conditions and additional uses for existing medications.

Scientist using microscope for analysis in lab
GoodRx created its list by prioritizing "first-in-class medications and vaccines that are expected to have a significant impact on human health." (iStock)

Here is the list in order of FDA approval date.

Eosinophilic esophagitis (an allergic condition that causes inflammation of the esophagus) is an additional use for Dupixent.

2. Amtagvi – New medication: Advanced melanoma

3. Xolair – Additional use: Food allergies

4. Wegovy – Additional use: Cardiovascular risk reduction

5. Tryvio – New medication: High blood pressure

6. Nexletol – Additional use: High cholesterol

Close-up of hands organizing medication into daily pill organizer
Some medications offer new treatments for common conditions, like Tryvio for high blood pressure and Nexletol for high cholesterol. (iStock)

7. Winrevair – New medication: Pulmonary arterial hypertension

8. mRESVIA – New vaccine: RSV

9. Capvaxive – New vaccine: Pneumococcal disease

10. Wakix – Additional use: Pediatric narcolepsy

11. Ohtuvayre – New medication: COPD

12. Kisunla – New medication: Alzheimer's disease

Heartburn from non-erosive GERD (gastroesophageal reflux disease) can be managed with additional use of Voquezna.

Medical professional preparing injection of vaccine or treatment
Some newly approved medications are administered via injection, like Kisunla for Alzheimer's and Dupixent. (iStock)

14. Zunveyl – New medication: Alzheimer's disease

15. Hypoparathyroidism (low levels of the parathyroid hormone) is a new medication called Yorvipath.

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16. Neffy – New medication: Severe allergic reactions

17. FluMist – Additional use: Self- or caregiver-administration

18. Cobenfy – New medication: Schizophrenia

19. Dupixent – Additional use: COPD

woman using a nasal spray in her bedroom
Many of the newly approved drugs are nasal sprays, like FluMist, a nasal spray vaccine that helps prevent the flu, and Neffy, which is used to treat life-threatening allergic reactions. (iStock)

GoodRx created a list of first-in-class medications and vaccines that are expected to have a significant impact on human health, according to a disclaimer.

The company defined the number of lives touched or the expected degree of impact for future medication recipients as the measure of success.

"We prioritized medications with notable advantages over those recommended by clinical treatment guidelines or mainstay medical organizations based on effectiveness or safety data."

Planet Chronicle Digital reached out to GoodRx for comment.

by Angelica Stabile

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